In quiz mode, labels and description will be hidden. Study Mode. The calcified bone is purple. The non-calcified elements are light blue. Find areas of compact bone and trabecular bone. This slide shows endochondral ossification, the process by which cartilage is calcified to form bone. Begin by distinguishing bone from the surrounding muscle tissue and from the cartilage epiphyses.
Indicate the regions in which cartilage is being concerted into bone. Identify the specific areas where chondrocytes are resting, proliferating, maturing, undergoing hypertrophy, and calcifying. Pathology Please select whether to view the slides in study mode or quiz mode.
Quiz Name the precursor to this cell. Answer: This is an osteocyte, which is an osteoblast that has become encased in bone. The embryonic precursor to both of these is the osteoprogenitor cell, a mesenchymal stem cell. Answer: Lysosomal hydrolases, collagenase, acid pH. Answer: Epiphyseal Plate. Answer: Bone remodeling.
Answer: Endochondral Ossification. Answer: This is an osteoclast, which resorbs bone. It's embryological precursor is a monocyte. In contrast, the precursors of osteoblasts are mesencyhmal stem cells. Answer: Osteoclast activation requires a previous osteoblast activation. The femur and tibia already bear the weight of most of the body; small accidents, like simple falls, can result in injury.
In spongy bone, trabeculae—small struts that are separated by cavities filled with marrow—become thinner and the spaces between them become wider, causing an overall weakening of bone structure. While you know that milk is rich in calcium and vitamin D, the two most important nutrients for bone health, it's not the only one! Leafy greens like spinach, kale, and okra are high in calcium. Fatty fish like tuna and salmon, as well as cheese and egg yolks, are vitamin D-rich foods.
So the next time you're watching TV and Sally Field tells you that you need to eat things rich in calcium and vitamin D, you should listen. You should listen to her anyway, because she's awesome.
Be sure to subscribe to the Visible Body Blog for more anatomy awesomeness! Are you a professor or know someone who is? We have awesome visuals and resources for your anatomy and physiology course! Learn more here. Additional Sources:. When you select "Subscribe" you will start receiving our email newsletter.
Use the links at the bottom of any email to manage the type of emails you receive or to unsubscribe. See our privacy policy for additional details. Welcome to the Visible Body Blog! Your skeleton's awesome—no bones about it! I couldn't resist. Compact Bone Cortical Bone Compact bone is dense bone tissue found on the outside of a bone.
Spongy Bone Cancellous Bone "Cancellous" makes it sound so negative, doesn't it? Bone Marrow and Stem Cells You've been bombarded by headlines about stem cells over the past decade, but what do they actually do? Osteoporosis I drink seven or eight thousand glasses of milk a day. Subscribe Here! Also in this section, note the empty lacunae and canaliculi that housed the osteocyte and its cell processes, respectively.
Slide 11 Nasal mucosa. Intramembranous ossification is visible in the nasal conchae on this slide. Bone arises directly within mesenchymal condensations.
This process can be identified by the appearance of bone spicules islands of bone among mesenchymal cells.
Look for the eosinophilic bone matrix. The surrounding mesenchymal cells are stellate in appearance. Endochondral bone formation is represented in this slide. Bone arises by replacement of a small hyaline cartilage model. Locate the epiphyseal plate ; it is the site for bone elongation. First, find the hyaline cartilage and move toward the bone marrow. Identify the 5 overlapping zones:. Zone of Reserve or Resting Cartilage - young small cells evenly distributed, appears as typical hyaline cartilage.
Zone of Cell Proliferation - chondrocytes divide, forming parallel columns. Zone of Cell Maturation and Hypertrophy - cells produce collagen and ground substance.
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